Mounjaro的获批用途 1. 2型糖尿病管理——Mounjaro获批作为饮食与运动的辅助疗法，帮助2型糖尿病成人降低血糖水平。
Mounjaro
Mounjaro is the brand name for a prescription medication whose active ingredient is tirzepatide — a novel injectable treatment approved to improve blood sugar control in adults with type 2 diabetes mellitus when used alongside diet and exercise. (Mounjaro)
Mounjaro is administered once weekly via a subcutaneous injection (under the skin) and has gained attention for also producing weight loss effects in clinical settings — a benefit closely associated with its mechanism of action. (Cleveland Clinic)
How Mounjaro Works (Mechanism of Action)
Mounjaro (tirzepatide) is a dual incretin receptor agonist, meaning it activates two key hormones involved in glucose regulation:
✔ GLP-1 (Glucagon-Like Peptide-1) — increases insulin release and slows digestion
✔ GIP (Glucose-Dependent Insulinotropic Polypeptide) — enhances insulin secretion and improves metabolic signaling
This dual action leads to improved insulin sensitivity, reduced blood sugar levels, slowed gastric emptying, lowered appetite, and often weight reduction in users. (European Medicines Agency (EMA))